The basis of the treatment of onychomycosis is the use of topical preparations. They quickly penetrate the structure of the keratin layer, reach its bed and destroy the filaments of the mycelium. Along with this, drugs with antimycotic effect kill pathogenic spores, so you can not be afraid of a quick relapse of the disease. The range of antifungal drugs for external use is divided into two categories – expensive and cheap. Each of them has its own leaders. Consider the most effective creams, ointments and gels, sold at a low price and coping well with the task.
Classification of antimycotic drugs
According to the principle of action, local antimycotics are classified as specific fungicidal or keratolic agents. The composition of the first is aimed at suppressing the activity of the pathogen and its gradual destruction. The second act radically – accelerate the rejection of diseased areas of the nails or skin. This method is used in the later stages of the disease when it is no longer possible to save the plate.
According to the active substance, they are also divided into allylamine and azole. The former destroy fungal colonies, and the latter interferes with the further propagation of the pathogen. Gradually, both types of drugs lead to the death of the infection. Therapy with allylamine ointments or creams takes up to three months, and with azole ones – 30 days. Although the latter are considered inexpensive drugs, the components of the former accumulate inside the nails faster, which reduces the likelihood of a return of the disease.
Regardless of the type of medicine chosen, treatment is carried out according to the following rules:
- all affected areas are treated at the same time;
- when applying the drug, neighboring tissues are affected so that the pathogen does not pass to them;
- personal hygiene is strictly adhered to during therapy.
Before using the drug, the limbs are steamed in the bath. This activity helps to remove infected areas more easily. For this, disposable nail files or scissors are taken. Used tools cannot be used to work with healthy skin or nails. Preparation of tissues is carried out before each application of the ointment.
If after a few weeks the treatment does not give any result, you need to see a doctor.
Clotrimazole belongs to the azole group. One percent gels, creams and ointments are delivered to pharmacy chains. Their main component is the substance clotrimazole. The gel is sold in a package of 20 or 40 g. Cream and ointment are packaged in tubes with a capacity of 15, 20, 30 or 40 g. The active ingredient works against all common pathogens of mycosis, such as dermatophytes, dimorphic and yeast-like mushrooms. Clotrimazole prevents pathogenic cells from producing nucleic acids, which provokes the destruction of membranes and the death of pathogenic microflora.
External forms of the drug are intended primarily for the treatment of skin, but are also used for the treatment of onychomycosis. Clotrimazole is used against fungal erosion, trichophytosis, epidermophytosis, microsporia and other types of lesions. The drug copes with pathogens that cannot be eliminated by nystatin therapy. Gel, cream and ointment are prescribed to eliminate and prevent thrush. Clotrimazole prevents the development of secondary infections of female intimate organs.
External agents are characterized by poor absorption in the circulatory system, and therefore such drugs do not have a general effect on the body. Clotrimazole has no contraindications, with the exception of individual intolerance to the active substance. Side effects are represented by local reactions. In some patients, standard allergy manifestations, such as burning, peeling and edema, were recorded, only some formed blisters and erythema started.
External types of clotrimazole are used according to the instructions. On steamed, cleaned and dried areas, the medicine is applied in a thin layer up to three times a day. The duration of treatment is determined by the rate of disappearance of the signs of the disease. When the symptoms disappear, a cream from the fungus or ointment will need to be smeared for two weeks in order to avoid relapse of the pathology.
External forms of clotrimazole are considered the cheapest antimycotic drugs. The price for packaging does not exceed 80 rubles.
The drug is released in the form of tablets, spray, cream and ointment. In each form of the drug, terbinafine hydrochloride is the active ingredient. The cream looks like a homogeneous mass of white with a pronounced smell. Auxiliary elements:
- benzyl alcohol;
- stearic acid;
- petroleum jelly;
Vaseline oil, propylene glycol, carbomer, polysorbate, sodium hydroxide, methyl parahydroxybenzoate and water are added to the ointment.
The active substance acts similarly to clotrimazole. All forms of terbinafine work against the same groups of pathogens through the gradual destruction of the cell membrane. The drug inhibits the synthesis of ergosterol, as a result of a deficiency of which the content of squalene increases. Such changes lead to the shutdown of the enzyme systems of the pathogenic cell and its further death.
Ointment and cream are prescribed for toenail fungus, which is caused by yeast, mold and dermatophytes. Doctors recommend external forms against candidiasis, but drugs also cope with other types of mycosis pathogens.
Terbinafine is banned for individual sensitivity and requires additional specialist advice for renal and hepatic insufficiency, alcoholism and hematopoiesis.
Instructions for the use of Terbinafine states that only a tablet form has numerous contraindications and negative effects. External types of antimycotics can provoke only local reactions, such as hyperemia, itching and burning.
On the prepared keratin layers, the ointment is applied twice a day with light rubbing movements. For the complete disposal of the nail plates from mycosis, it may take up to six months.
The average cost of packing Terbinafine ointment is 80 rubles.
Thermicon is the best and most inexpensive ointment, a direct analogue of Terbinafine, made from the same active substance. A medicine with fungistatic, antifungal and fungicidal effects is supplied to drugstore counters in tubes of 15 g each. The ointment is indicated for use in multi-colored lichen, the first stages of inguinal epidermophytosis, foot mycosis and smooth skin. It is permissible to use Thermicon as a prophylaxis. Therapy with this remedy can last up to a year, depending on the characteristics of the disease.
The medicine is contraindicated in:
- carrying a child and breastfeeding;
- children under three years old;
- individual intolerance to the composition;
- malignant neoplasms;
- renal and hepatic impairment;
- metabolic diseases;
- oppressed blood formation;
- pathologies leading to vascular occlusion.
Thermicon provokes numerous side effects, but they are all local in nature.
The price of ointment in pharmacies is 150-250 rubles.
Belongs to the keratolic type of funds. According to the description, the drug helps to remove the affected areas of the nails, so that later healthy keratin grows instead. Fundisol consists of the following natural ingredients:
- zinc oxide;
- petroleum jelly;
- salicylic acid;
- potassium iodide;
- oak bark;
- purified water.
Most ingredients are aimed at softening and disinfecting surfaces. The composition also contains nipagin with antiseptic and antibacterial properties and nipazole, which destroys mold fungi. Fundisol softens the tissues, so they are faster removed. The drug establishes the work of sweat glands, fights inflammation and promotes regenerative processes.
If the nails are damaged, you need to smear the medication with a thick layer, using an applicator or a cotton swab. On top of Fundizol is applied compression paper, which is fixed with a patch. The dressing is removed after six hours. The procedure is carried out twice daily. Treatment is completed when a healthy nail appears. Sometimes this process takes up to six months.
The price of antimycotics is relatively low – 160-180 rubles.
The list of medicines that kill the fungus in the nails includes mainly expensive products, the price of which is above 400 rubles. If you need to effectively solve the problem by cheap methods, then you can use Nogtimycin. The action of this drug is aimed at accelerated rejection of the plate affected by the fungus.
Nogthimycin is available in the form of a cream for external use with a volume of 30 ml. The composition includes:
- stearic and salicylic acids;
- propylene and decylene glycols;
- emulsion and beeswax;
- Castor oil;
- oils of lavender, peppermint, corn and kayeput;
The ingredients penetrate the nail and soften it, so that after several applications the plate can be removed without pain. The medicine works locally and does not penetrate the systemic circulation. Later, instead of a removed nail, a healthy plate grows. The medication can not be used with individual sensitivity to active substances, including bee products, and with open wounds in the treated area.
The procedure is carried out similarly to the use of therapeutic ointment, but the tissue around the diseased area needs to be protected with a patch. Nogthimycin is applied in a thick layer and sealed. The compress is left on the nail for up to four days. After the time has passed, the bandage is removed, the legs are steamed with the addition of soda and soap. During the procedure, it will be possible to carefully remove the exfoliated part of the plate. If the nail does not come off completely, it is necessary to repeat the treatment according to the rules given in the instructions.
Nogtimycin is a domestic drug that can be purchased at a pharmacy for 100-200 rubles.
If the patient does not want to spend money on the purchase of specialized antimycotic drugs, he can turn to antiseptic agents. Some people treat mycosis with salicylic ointment. The medication does not affect the cells of the fungi, but fights inflammation, helps to heal tissues and has keratolytic properties. Salicylic ointment will not cure the nail, but will accelerate its removal. The cost of the tool is only 30 rubles.
Provided that it is combined with other antimycotic drugs, it is permissible to treat with sulfuric ointment. In complex therapy, it is able to reduce the manifestations of mycoses. Sulfur has antimicrobial, antiseptic and antiparasitic properties, but does not directly affect mycoses. The medication has a pronounced irritating effect and costs from 20 to 40 rubles.
At home, the fungus is treated with vinegar or iodine. The first forms an acidic environment in which the pathogen cannot live. To protect the skin from burns, vinegar is combined with sunflower oil, eggs and dimethyl phthalate, which is purchased at the pharmacy. Nails are treated with iodine to enhance the properties of other antifungal agents. The drug can be mixed with celandine juice.
Rating of expensive broad-spectrum products
Most drugs against nail fungus belong to the high price segment, but such drugs can achieve a lasting result without subsequent relapses. Expensive drugs from the allylamine group are represented by Lamisil, Exoderil, Nizoral and Mykosan. The first is made from terbinafine hydrochloride and is used locally.
Exoderil ointment and cream is created from naphthyne hydrochloride and a number of standard excipients. The drugs have a one percent concentration and are packaged in aluminum tubes of 15 or 30 g. Exoderil has a fungicidal, fungistatic and antimycotic effect.
Cream from nail fungus is applied twice a day. Sometimes it takes up to six months to expect a result. In rare cases, exoderil provokes increased dryness of the skin, leading to swelling and burning. Side effects do not require discontinuation of treatment and soon pass on their own.
The active substance of Nizoral is ketoconazole. The drug is indicated for fungal skin lesions, but has a weak effect on the nails.
The cost of the transferred funds reaches 600 rubles.
To eliminate onychomycosis, it is recommended to use varnishes, such as Mycosan. The action of the product, made on the basis of a filtrate from the rye enzyme, is aimed at eliminating nail fungus and protecting against secondary infections.
The price of Mikozan in Russia varies from 600 to 900 rubles. As an analogue, varnishes Lamisil and Exoderil are considered.